Michael Uzick, N.M.D.

Naturopathic Physician

 
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Anti-oxidants, Chemotherapy and Radiation

If you are taking or considering taking nutritional or herbal supplements, your oncologist and particularly your radiation oncologist might insist that you don't.  The rational for avoiding supplemental nutrients, in particular, anti-oxidant nutrients, is that they will interfere with and reduce the effectiveness chemotherapy and radiation.

This theory seems to be logical, since the sole mechanism of action for radiation and for some chemotherapies, is the generation of free radicals.  Anti-oxidants help neutralize free radicals and thus we have a potential conflict.  However, it turns out this theory and its logic happen to be faulty.

If we look at literally hundreds of cell culture, animal and human studies on this subject, we find the the exact opposite is true.  Examining the entirety of mainstream medical and scientific literature, there is an overwhelming and consistent finding; anti-oxidants significantly increase the effectiveness and reduce the toxicity of chemotherapy and radiation.

However, there are exceptions. Interactions - particularly with herbal medicines - are possible. It is essential to seek the advice of an expert before utilizing supplements while undergoing conventional treatment for cancer.

Below is a link to an excellent research review article which goes through the scientific literature on this topic.

Antioxidants in Cancer Therapy; Their Actions and Interactions With Oncologic Therapies