Michael Uzick, N.M.D.

Naturopathic Physician

 
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Anti-oxidants, Chemotherapy and Radiation

If you are taking or considering taking nutritional or herbal supplements, your oncologist and radiation oncologist might insist that you don't.  The rational for avoiding supplemental nutrients, in particular, anti-oxidant nutrients, is that they will interfere with and reduce the effectiveness chemotherapy and radiation.

This theory seems to be logical if chemotherapy and radiation work by generating free radicals. Since anti-oxidants help neutralize free radicals, we might have a potential conflict. It's important to realize that only some chemotherapeutic agent work by this mechanism. More importantly, it turns out this theory and its logic happen to be faulty.

If we look at literally hundreds of cell culture, animal and human studies on this subject, we find the the exact opposite is true. Examining the entirety of mainstream medical and scientific literature, there is an overwhelming and consistent finding; anti-oxidants significantly increase the effectiveness and reduce the toxicity of chemotherapy and radiation.

However, there are exceptions. Interactions - particularly with herbal medicines - are possible. It is essential to seek the advice of an expert before utilizing supplements while undergoing conventional treatment for cancer.

Below are links to an excellent research review articles which goes through the scientific literature on this topic.

Antioxidants in Cancer Therapy; Their Actions and Interactions With Oncologic Therapies

Antioxidants and other nutrients do not interfere with chemotherapy or radiation therapy and can increase kill and increase survival, Part 1

Antioxidants and other nutrients do not interfere with chemotherapy or radiation therapy and can increase kill and increase survival, Part 2